Low-dose therapy for the control of infl ammation

Journal title PNEI REVIEW
Author/s Massimo Fioranelli, Paola Petrelli, Maria Grazia Roccia
Publishing Year 2017 Issue 2017/2
Language Italian Pages 12 P. 59-70 File size 1120 KB
DOI 10.3280/PNEI2017-002006
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Low grade chronic inflammation (LGCI) is a very common condition; the incidence is proportional to age. Patients with chronic inflammatory disease have a higher risk of cardiovascular disease (CVD) and related mortality. Cardiovascular risk factors are of course a key factor for the onset of CVD; however, LGC acts independently: it accelerates atherosclerosis, favors myocardial infarction, cerebrovascular disease and heart failure (HF). Modulation of systemic system inflammation goes through various interventions: nutrition, exercise, microbiota control, stress modulation. A promising role is attributed to low-dose therapy that uses low doses of natural principles and biological molecules such as cytokines, neuropeptides, hormones and growth factors.

Keywords: Chronic inflammation, low-grade inflammation, cardiovascular diseases, microbiota, mitochondria, low-dose therapy

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Massimo Fioranelli, Paola Petrelli, Maria Grazia Roccia, Terapia low-dose per il controllo dell’infi ammazione in "PNEI REVIEW" 2/2017, pp 59-70, DOI: 10.3280/PNEI2017-002006